Detecting All Cancers Earlier

 

Vidcast:  //youtu.be/iOVqB2XL6VU

 

Glycosaminoglycans are sugars that undergo unique structural changes when normal cells become malignant.  Swedish researchers now report the results of their multisite, international study that successfully detected all 14 different types of cancer that were under investigation.  Comparing the detection of altered glycosaminoglycans with neoplasm DNA fragment detection as a means of implementing so called Multi-Cancer Early Detection or MCED, the investigators were heartened to find that the sugar analysis detected more types of cancer at the earliest stages than DNA detection.   The best news: glycosaminoglycan analysis is relatively cheap opening up the possibility of its wide application.  The technique is being commercialized by the startup Elypta, a Chalmers University of Technology spinoff.

 

//www.pnas.org/doi/10.1073/pnas.2115328119

 

#cancer #glycoaminoglycans #sugar #polysaccarides #oncology #earlydetection #mced